Neural Stem Cells and their Niches in Neuroregeneration
نویسندگان
چکیده
منابع مشابه
Stem cells and their niches.
A constellation of intrinsic and extrinsic cellular mechanisms regulates the balance of self-renewal and differentiation in all stem cells. Stem cells, their progeny, and elements of their microenvironment make up an anatomical structure that coordinates normal homeostatic production of functional mature cells. Here we discuss the stem cell niche concept, highlight recent progress, and identify...
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In mammalian tissues, aging typically is accompanied by a progressive loss of homeostasis and impairment of regenerative potential. This association argues for a particular focus on changes that occur in the body’s stem and progenitor cells with age because it is the primary role of these cells to maintain and regenerate tissue function throughout life. 1)Hematopoietic stem cells Within adult t...
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The adult central nervous system (CNS) is a tissue with a low rate of renewal and can be seriously affected by injuries and diseases. The generation of new neural cells, such as neurons and glia, is prevalently restricted to specific CNS areas (niches) deriving from embryonic germinative layers. Continual neurogenesis is sustained by multipotent astro/radial glia-like neural stem/precursor cell...
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Background: This article reviews experimental and clinical studies in which neural injuries repaired with bone marrow stromal cells. History: Bone marrow contains two kinds of stem cells: hematopoietic and nonhematopoietic (stromal) stem cell. In vitro studies indicate that bone marrow stromal cells have the capacity of differentiation into other cells (such as neural cell) under treatment wit...
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ژورنال
عنوان ژورنال: International Journal of Stem cell Research & Therapy
سال: 2015
ISSN: 2469-570X
DOI: 10.23937/2469-570x/1410015